DTC codes / P21xx · Fuel and air metering / P216A
P216A indicates that the powertrain control module has detected an abnormal voltage condition on the power supply circuit feeding fuel injector group E, which is a set of injectors wired together on a shared feed. The circuit is open or has excessive resistance, so the injectors in that group may not receive the current needed to fire reliably.
Guidance is general and written for all OBD-II vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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