P1681 on GM vehicles indicates that the powertrain control module (PCM) has detected a fault on the serial data communication line it uses to talk to the electronic throttle control (ETC) module, often called driver 5 line 1. The PCM monitors this dedicated data circuit for expected messages and voltage levels, and it sets the code when the signal is missing, corrupted, or out of range, which can affect throttle response and other functions.
If the vehicle is in reduced power mode or the throttle response is unpredictable, avoid driving and have it towed to a repair shop. If the only symptom is a warning light and the car drives normally, you can drive cautiously to a service location, but avoid heavy acceleration or towing until the fault is repaired.
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Guidance is general and written for GM vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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