P1295 on a GM vehicle means the powertrain control module (PCM) has detected a loss of the 5-volt reference voltage supplied to the throttle position (TP) sensor circuit. The PCM monitors this reference line and sets the code when the voltage drops below a calibrated threshold, which prevents it from accurately reading throttle position.
You can drive the vehicle to a repair shop if the engine runs normally and the check engine light is the only symptom, but avoid heavy acceleration or towing. If the engine enters limp mode or stalls, stop driving and have the vehicle towed to prevent unsafe conditions.
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Guidance is general and written for GM vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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