P1280 on a GM vehicle indicates that the powertrain control module has detected an out-of-range or implausible signal from the accelerator pedal position sensor 2 circuit. The computer compares this signal against sensor 1 and expects a specific voltage relationship, so a deviation triggers the code and typically forces the engine into reduced power mode.
You can usually limp the vehicle to a shop, but expect reduced power and avoid highways or heavy traffic because throttle response may be unpredictable. If the pedal feels dead or the engine idles high on its own, stop driving and have it towed.
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Guidance is general and written for GM vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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