P1278 on a GM vehicle means the engine control module (ECM) has detected an abnormally high voltage on the signal circuit from accelerator pedal position sensor 1, which is one half of the redundant pedal assembly. The ECM expects this sensor's output to stay within a calibrated low-voltage range that rises smoothly as the pedal is pressed, and a sustained high reading tells the module the circuit is shorted to voltage or the sensor has failed internally.
The vehicle is usually safe to drive to a shop, but expect reduced power and a throttle that may not respond normally, so avoid highway merging and heavy traffic until it is repaired. If the pedal goes completely unresponsive, stop driving and have the vehicle towed.
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Guidance is general and written for GM vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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