DTC codes / U00xx · Network wiring and bus faults / U0066
U0066 indicates that the vehicle's communication network has detected an open circuit on the positive (high) side of Bus E, meaning the data wire is physically broken or disconnected somewhere along its path. The computer expects a continuous electrical path for the bus to function, and when that path is interrupted, it logs this code and typically disables communication with the modules on that bus.
If the vehicle starts and runs normally, you can drive it to a repair shop, but avoid relying on any features that use Bus E, such as advanced driver aids or certain body functions. If the engine stalls or multiple critical systems fail, stop driving and have the vehicle towed to prevent unsafe operation.
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Guidance is general and written for all OBD-II vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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