P1216 on a Kia indicates that the engine control module (ECM) has detected an abnormally high voltage on the control circuit for fuel injector number 4. This typically means the circuit is open, shorted to power, or the injector coil has failed, preventing the ECM from properly energizing the injector.
Driving with P1216 is possible but not recommended because a misfiring cylinder can damage the catalytic converter over time. Avoid heavy acceleration and have the vehicle inspected promptly.
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Guidance is general and written for Kia vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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