P1538 on a GM vehicle means the powertrain control module (PCM) has detected an abnormally high voltage on the air conditioning request circuit, which is the signal wire from the HVAC control head to the PCM. The PCM expects this circuit to rest at a low reference voltage and pull low when A/C is requested, so a sustained high voltage tells the module the request line is open, shorted to voltage, or the control head is not pulling it down.
You can keep driving with P1538 because the fault affects only the air conditioning request signal and does not compromise engine safety or drivability. Avoid relying on A/C operation until the circuit is repaired, and have the wiring inspected soon to prevent a simple connector fault from turning into a control head or PCM replacement.
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Guidance is general and written for GM vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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