P1352 on a GM vehicle means the ignition control module (ICM) has detected an unexpected high voltage pulse on the cylinder 2 ignition control circuit while that circuit is supposed to be grounded. The computer commanded the coil for cylinder 2 to fire, but the feedback signal showed the circuit stayed high when it should have been pulled low, indicating a fault in the ignition coil, wiring, or ICM itself.
You can usually drive the vehicle short distances to a repair shop, but avoid heavy acceleration or towing because a persistent misfire can overheat the catalytic converter. If the check engine light is flashing, stop driving and have the vehicle towed to prevent converter damage.
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Guidance is general and written for GM vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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