P1222 on a GM vehicle means the engine control module (ECM) has detected an intermittent fault in the electrical circuit that operates one or more fuel injectors. The ECM monitors injector command and feedback circuits and flags this code when the circuit momentarily opens, shorts, or behaves erratically without staying failed long enough to set a hard circuit code.
You can usually drive short distances to a repair shop, but avoid heavy acceleration, towing, and long trips until the intermittent circuit is found because a sudden injector dropout can cause a misfire, power loss, or stall. If the engine begins running rough continuously or the check engine light starts flashing, stop driving and have the vehicle towed.
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Guidance is general and written for GM vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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