P1143 on a GM vehicle means the powertrain control module (PCM) has detected that the downstream heated oxygen sensor (HO2S) on bank 1, sensor 3 is reporting a lean condition or a voltage that stays lower than expected. The PCM monitors this sensor after the catalytic converter to judge catalyst efficiency and fuel control, and it sets the code when the signal remains below the calibrated lean threshold for too long.
You can usually drive the vehicle with P1143 set, but avoid heavy acceleration and long trips until it is diagnosed because a persistent lean condition can overheat the catalytic converter. If the check engine light starts flashing or you notice misfiring, stop driving and have it inspected immediately.
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Guidance is general and written for GM vehicles. Exact tests and values vary by model, so confirm the fault before replacing parts.
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